Trps1 breast
WebNov 18, 2024 · TRPS1 is a sensitive and specific marker for metastatic breast cancer in serous effusion cell-block specimens. It shows superior sensitivity and specificity compared with GATA3, especially in the TNBC setting and for excluding urothelial carcinoma. CONFLICTS OF INTEREST The authors made no disclosures. WebJul 3, 2024 · The GATA transcription factor TRPS1 is abnormally up-regulated in breast cancer, osteosarcoma, prostate cancer, and other tumor tissues, and is instrumental in regulating cell proliferation, differentiation, and tissue growth and development. Methods
Trps1 breast
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WebApr 1, 2024 · As shown in Fig. 1, a high mRNA level of TRPS1 was observed in breast carcinoma only, among the 31 types of solid tumors; moreover, the mRNA level of TRPS1 showed equally high expression in all four subtypes of breast carcinoma including ER/PR-positive luminal A and B types, HER2-positive, and basal types (which are predominantly … WebMar 9, 2024 · TRPS1 is amplified/overexpressed in breast cancer and promotes breast carcinogenesis (A) Tissue array analysis for TRPS1 expression (left). ∗∗∗ p < 0.001; two-tailed paired t test. Representative images are shown (right). (B) Western blotting analysis of TRPS1 expression in the indicated cell lines.
WebNov 11, 2024 · In this study, overexpression of lncRNA178030.2 significantly attenuated the inhibitory effect of 1 μM paclitaxel in cell proliferation of MDA-MB-231, while knockdown of lncRNA178030.2 had an opposite effect, suggesting that lncRNA178030.2 mediated the process of paclitaxel resistance of breast cancer cells. TRPS1 is a newly discovered … WebJul 3, 2024 · The GATA transcription factor TRPS1 is abnormally up-regulated in breast cancer, osteosarcoma, prostate cancer, and other tumor tissues, and is instrumental in …
WebMar 11, 2016 · TRPS1 was frequently down-regulated in high-metastatic cancer cell lines from the breast, colon and nasopharynx. Silencing of TRPS1 stimulated epithelial–mesenchymal transition (EMT), migration and invasion in vitro and metastasis in vivo , while TRPS1 over-expression exhibited the opposite effects. WebOct 25, 2024 · MGP, TRPS1, and GATA3 could be applied as a reliable diagnostic panel to determine breast origin in clinical practice. Introduction Breast cancer is the most common cancer among women worldwide. Approximately 5.8% of female breast cancers have distant metastasis at diagnosis (de novo stage IV breast cancer) [ 1 ].
WebMar 1, 2024 · We tested TRPS1 expression in 21 cases of primary sarcoma of the breast which included 10 UPSs, 2 liposarcomas, 2 leiomyosarcomas, and 7 chondrosarcomas …
WebTRPS1抑制SOX2在乳腺癌细胞干性维持和肿瘤发生起始的转录调控机制研究.pdf hillingdon abbots rfcWebMay 5, 2008 · Individuals with TRPS1 may also exhibit other physical abnormalities including abnormal prominence of the breast bone (pectus carinatum), an unusual “wing-like” shape … hilling tomatoesWebIn the current study, through TCGA data mining we identified trichorhinophalangeal syndrome type 1 (TRPS1) as a specific gene for breast carcinoma across 31 solid tumor types. Moreover, high mRNA level of TRPS1 was found in all four subtypes of breast carcinoma including ER/PR-positive luminal A and B types, HER2-positive type, and basal … hilling-pfeffer insurance agencyWebAug 2, 2024 · TRPS1 regulates HDAC2 protein level by stabilizing HDAC2 in ubiquitin-dependent proteasomal degradation (UDPD) Analysis of TRPS1 interactome had … smart factory event drachtenWebOct 30, 2024 · TRPS1 as Both an Activator and a Repressor of Transcription in Breast Cancer Because TRPS1 is a TF that may directly regulate genes required for G2-M progression and survival in breast cancer cells, we performed RNA-seq of HCC3153 and SUM159 cell lines 3, 4, and 5 days after inducing TRPS1 knockdown. smart factory expo 2021 liverpoolWebApr 3, 2024 · TRPS1 (trichorhinophalangeal syndrome type 1) is a transcription factor of the GATA family, and has been found to be a relatively specific marker of breast cancers through TCGA (The Cancer Genome Atlas) data mining [].It is not only expressed in a high proportion of ER-positive or HER2-positive BCs, but also in TNBCs of different types, … hilling potatoes in gardenWebAug 10, 2024 · Involved in breast cancer carcinogenesis and required for breast cancer cell survival Plays a critical role in the development of cartilage, bone and hair follicle ... hillingdon abbots ladies fc