WebAug 19, 2024 · Principally stored in the liver and bone marrow, also stored in the kidneys and adrenals Metabolism Converted in tissues to active coenzymes, methylcobalamin and deoxyadenosylcobalamin; undergoes some enterohepatic recycling Excretion Urine (50% to 98%, unchanged drug) Onset of Action Megaloblastic anemia: IM: WebApr 3, 2024 · Cyanocobalamin Injection, USP is a sterile solution of cyanocobalamin for intramuscular or subcutaneous injection. Each mL contains 1,000 mcg cyanocobalamin, Sodium Chloride 0.9%. Benzyl Alcohol 1.5% is present as a preservative. ... Research indicates that patients with impaired kidney function, including premature neonates, …
CYANOCOBALAMIN INJECTION, USP - DailyMed
WebCyanocobalamin (Vitamin B-12) Deficiency: Daily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin. ... moderate or severe renal impairment compared to healthy subjects with normal renal function. Patients with Hepatic Impairment: In patients with mild (Child-Pugh Class A) or moderate (Child ... the go above the in the source code file
B vitamin therapy for homocysteine: renal function and …
WebCyanocobalamin is indicated for vitamin B12deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation WebVitamin B12, also called cobalamin, is one of 8 B vitamins. All B vitamins help the body convert food (carbohydrates) into fuel (glucose), which is used to produce energy. These B vitamins, often referred to as B complex vitamins, also help the body use fats and protein. B complex vitamins are needed for healthy skin, hair, eyes, and liver. WebLoss of kidney function can cause a buildup of fluid or body waste or electrolyte problems. Depending on how severe it is, loss of kidney function can cause: Nausea Vomiting Loss of appetite Fatigue and weakness Sleep problems Urinating more or less Decreased mental sharpness Muscle cramps Swelling of feet and ankles Dry, itchy skin the gnurrs come from the voodvork out