Web开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 WebMar 1, 2024 · To further characterize the effects of adipocyte-specific deficiency of Nfe2l1 on glucose and lipid metabolism, we measured the plasma levels of glucose, TG and …
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WebNov 22, 2024 · Although treatment with CL316243 could improve the metabolic capacity of mice, the respiratory metabolic capacity of Trib1-knockout mice was still lower than that of the wild-type control under CL316243 treatment (Fig. 3g, h). We also evaluated the BAT thermogenesis of mice by cold adaptation. WebJun 5, 2015 · Male C57BL/6J mice were singly housed at 30°C or 22°C and treated with vehicle or CL316243, a β3‐agonist, for 4 weeks. Food intake, energy expenditure, body and adipose weight, brown adipose activity, white adipose browning, and glucose tolerance were evaluated. CL316243 treatment was studied in both chow‐ and high‐fat diet‐fed mice.
WebJun 5, 2015 · Male C57BL/6J mice were singly housed at 30°C or 22°C and treated with vehicle or CL316243, a β3‐agonist, for 4 weeks. Food intake, energy expenditure, body … WebIt is well documented that CL316243-mediated activation of brown and beige adipose tissue upregulates genes involved in mitochondrial biogenesis, thermogenesis, mitochondrial electron transport ...
WebThis finding is not borne out by the functional phenotype of iWA, as rosiglitazone treatment significantly increases glucose uptake in response to norepinephrine and CL316243 . This reflects our observation that the limiting step in agonist-stimulated glucose uptake is the abundance of the β 3 -AR, which is markedly enhanced when iWAs are ... WebOur study suggests that CL improves glucose tolerance and lowers lipid profiles in the high-fat diet-feeding of rats by activating the AMPK/PGC-1α pathway. This finding supports …
Webadipose activity, white adipose browning, and glucose tolerance were evaluated. CL316243 treatment was studied in both chow- and high-fat diet-fed mice. Results: Mice at 308C, compared to 228C, had reduced food intake, metabolic rate, and brown adipose activity, as well as increased adiposity. At both temperatures, CL316243 treatment increased ...
WebMar 1, 2024 · To further characterize the effects of adipocyte-specific deficiency of Nfe2l1 on glucose and lipid metabolism, we measured the plasma levels of glucose, TG and glycerol in juvenile mice. While the blood glucose and TG in plasma were comparable between the genotypes, the plasma glycerol levels following a 16-hr overnight fasting displayed a … the voice 2022 ratingsWebJul 3, 2024 · When 3T3-F442A cells were exposed to CL316243, β1- and β2-ARs were blocked with CGP-20712 (500 nM) and ICI-118551(100 nM), respectively, to ensure that CL316243 exclusively activated β3-ARs. the voice 2022 remaining contestantsWebThe inhibition of insulin-induced glucose uptake by β 3-adrenergic prestimulation could be mimicked with dibutyryl cAMP and forskolin treatment (Fig. 7 C). Additionally, the … the voice 2022 results top 5WebNov 1, 2000 · In contrast with wild-type mice, treatment of A-ZIP/F-1 mice with CL316243, a beta3-adrenergic agonist, did not increase O2 consumption. A single dose of CL316243 … the voice 2022 schedule todayWebAt both temperatures, CL316243 treatment increased brown adipose activation and energy expenditure and improved glucose tolerance. At 30°C, CL316243 increased energy … the voice 2022 runner upWebAdipokines participate in the regulation of glucose and lipid metabolism, energy homeostasis, feeding behavior, insulin sensitivity, ... In the first study, BAT activation was induced by administration of CL316243, a β3 adrenoceptor agonist in rats, and evaluated by 18 F-FDG-PET imaging (Mirbolooki et al., 2011). CL316243-induced activation of ... the voice 2022 latest episodeWebJun 5, 2015 · At both temperatures, CL316243 treatment increased brown adipose activation and energy expenditure and improved glucose tolerance. At 30°C, CL316243 … the voice 2022 season finale