Chitinase 3-like 1 promoter
WebSep 9, 2014 · Correlation of chitinase 3-like 1 single nucleotide polymorphisms and haplotypes with uterine cervical cancer in Taiwanese women PLoS One. 2014 Sep 9 ... G/A), rs10399805 (-247, G/A) and rs4950928 (-131, C/G) in the promoter region, and one SNP rs880633 (+2950, T/C) in exon 5 were analyzed by real time polymerase chain … WebChitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein member of the glycoside hydrolase 18 chitinase family that targets chitin …
Chitinase 3-like 1 promoter
Did you know?
WebMolecular characterization of the Ym1 promoter in transfected epithelial and macrophage cell lines revealed the presence of multiple signal transducers and activators of transcription 6 (STAT6) response elements that function in a combinatorial manner to mediate transcriptional responses to IL-4 [2].
WebApr 5, 2024 · Chitinase-3-like Protein 1 (YKL-40): A New Biomarker of Inflammation in Pyoderma Gangrenosum. Peripheral blood mononuclear cell response to YKL-40 and Galectin-3 in cystic fibrosis. Chitinase 3-like 1 is involved in the induction of IL-8 expression by double-stranded RNA in airway epithelial cells. Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N-terminal amino acids present on the secreted form and its molecular mass. YKL-40 is … See more Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This … See more YKL-40 has been linked to activation of the AKT pro-survival (anti-apoptotic) signaling pathway. YKL-40 promotes angiogenesis through VEGF-dependent and independent … See more As Alzheimer's disease progresses, soluble amyloid beta aggregates in the brain can induce the activation of microglia, which triggers synthesis of pro-inflammatory mediators. This leads to increased Chi3l1 expression in astrocytes. There is evidence that YKL-40 levels … See more It is assumed that YKL-40 plays a role in cancer cell proliferation, survival, invasiveness and in the regulation of cell-matrix interactions. It is suggested that YKL-40 is a marker … See more • Human CHI3L1 genome location and CHI3L1 gene details page in the UCSC Genome Browser. See more • Rathcke CN, Vestergaard H (June 2006). "YKL-40, a new inflammatory marker with relation to insulin resistance and with a role in endothelial dysfunction and atherosclerosis". Inflammation Research. 55 (6): 221–7. doi:10.1007/s00011-006-0076-y See more
WebMar 21, 2024 · GeneCards Summary for CHI3L1 Gene. CHI3L1 (Chitinase 3 Like 1) is a Protein Coding gene. Diseases associated with CHI3L1 include Asthma-Related Traits 7 … WebChitinase 3-like 1: Products. Chitinase 3-like 1 (CHI3L1), also called BRP39 in mouse or YKL-40 in humans, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family …
WebChitinase 3-like-1 promotes intrahepatic activation of coagulation through induction of tissue factor in mice Authors Zhao Shan 1 , Xiaodong Liu 2 , Yuan Chen 1 , Meng Wang 1 , Yue Rachel Gao 1 , Liangguo Xu 1 , Wasim A Dar 3 , Chun Geun Lee 4 , Jack Angel Elias 4 5 , Pavel Davizon Castillo 6 , Jorge Di Paola 6 , Cynthia Ju 1 7 Affiliations
WebJan 27, 2024 · The Chi3l1 gene is located on human chromosome 1q32.1, which contains 7,948 bases and 10 exons. Its sequence is highly conserved and is primarily expressed in the liver, 15–227 times that in the human brain, heart, breast, and other organs. It is also a highly liver enriched gene ( 13 ). i can write the letter i can find the letterWebGenetic variation in chitinase 3-like 1 (CHI3L1) contributes to asthma severity and airway expression of YKL-40 In contrast to the promoter SNP rs4950928, the intronic SNP rs12141494 in CHI3L1 is associated with asthma severity, lung function, and YKL-40 expression in the blood and airway. i can write with both handsWebChitinase 3-like 1 (CHI3L1), also known as YKL-40 or human cartilage glycoprotein 39 (HC gp-39), is a 40-kD mammalian glycoprotein. The gene for CHI3L1 is located on … money belts for sale near meWebOct 19, 2015 · Here, we found that chitinase mRNA levels were 4.5-times greater when peanut seedlings were sprayed with 1.5 mM SA, as compared to water. The upstream … i can write to 120 worksheethttp://www.propriumbio.com/gbzdsj/info_159.aspx?itemid=9 i can write to 20 printableWebMar 28, 2024 · Chitinase 3 like 1 is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability. Crystal structure of breast regression protein 39 (BRP39), a signaling glycoprotein expressed during mammary gland apoptosis, at 2.6 A resolution. CHI3L1 regulates PD-L1 and anti-CHI3L1-PD-1 antibody elicits synergistic antitumor … i can write worksheetWebMar 15, 2009 · Aberrant expression of chitinase 3-like 1 (CHI3L1), also known as YKL-40 or HC gp-39, is involved in the pathogenesis of inflammatory and allergic diseases. Objectives: The genetic contribution of CHI3L1 gene to atopic susceptibility was investigated using an integrated population genetic and molecular analysis. money belts argos